GNRH1 and familial pancreatic carcinoma: Summarizing the results of our study, we can state that receptors for LH-RH are expressed in human pancreatic cancers, and that receptor-targeted therapy with the cytotoxic LH-RH analog, AN-152 (AEZS-108), has a stronger inhibitory effect on the growth of human pancreatic cancer lines in nude mice than the cytotoxic radical, DOX.