As shown in Table 2, TP53 rs78378222 was not associated with overall cancer risk (OR = 0.80; 95% CI = 0.58–1.11) in all cases combined, nor for risk of lung cancer (OR = 0.85; 95% CI = 0.48–1.53) and melanoma (OR = 1.10; 95%; CI = 0.68–1.77). The gene discussed is TP53; the disease is cancer.