As shown in Fig. 3C, TZM-bl cells pre-treated with C60 are still susceptible to HIV-1 Bal infection, while the cells pretreated with MiTMAB (a inhibitor of clathrin-mediated endocytosis) became resistant to the viral infection, suggesting that unlike MiTMAB, C60 does not interact with a cellular protein (e.g., clathrin or dynamin) to interfere with the cellular protein-regulated endocytosis process. Here, DNM1 is linked to viral infectious disease.