The reduction at end stage was significant (Figure 3D, lower panel, n = 6) In naive mice, CD1d was less expressed on BM cells compared to spleen cells (52%±2.1) and in tumor bearing mice, the expression declined in week 1 and week 2 (35%±7.2 and 43%±1.6 respectively) but did not decline further at the terminal point. Here, CD1D is linked to neoplasm.