Immunohistochemistry and Western blotting revealed that aspirin significantly up-regulated HTATIP2 expression in HepG2-wt tumor tissues, had a mild effect on HTATIP2 expression in HCCLM3-wt and HepG2-LV-HTATIP2, and had no effect on HTATIP2 expression in HCCLM3-LV-shHTATIP2 tumor tissues (Figure 4 A,B). Here, HTATIP2 is linked to neoplasm.