Arylacetamide deacetylase-like 1 (AADACL1) depletion increases atherosclerosis and cholesterol ester storage in murine macrophages (Sekiya et al, 2009), and its overexpression in THP-1 cells reduces cholesterol ester storage (Igarashi et al, 2010). This evidence concerns the gene NCEH1 and atherosclerosis.