ERBB3 and idiopathic dilated cardiomyopathy: In addition, Haas et al. [14] found an altered DNA methylation pattern in the myocardium of patients with idiopathic dilated cardiomyopathy, causing mis-expression of the genes for lymphocyte antigen 75 (LY75) and tyrosine kinase-type cell surface receptor HER3 (ERBB3), the zebrafish orthologs of which were found to be important for adaptive and maladaptive responses in heart failure.