EphA4 was an independent predictor of DSS on multivariate Cox proportional-hazards regression analysis (HR, 2.6; 95% CI, 1.1-6.3; p = 0.039, Table 5) adjusted for the following established clinical prognostic factors: depth of tumour (T4 versus T1-T3), lymph node metastasis, and histopathological type. This evidence concerns the gene EPHA4 and neoplasm.