EphA4 was an independent predictor of DSS (HR, 2.3; 95% CI, 1.1-4.8; p = 0.028) on multivariate Cox proportional-hazards regression analysis (Table 4) adjusted for the following established clinical prognostic factors: depth of tumour (T3-T4 versus T1-T2), lymph node metastasis, and histopathological type (undifferentiated versus differentiated). The gene discussed is EPHA4; the disease is metastatic malignant neoplasm in the lymph nodes.