ERBB2 and hepatocellular carcinoma: With regard to antitumor activity, mollugin has been shown to exert cytotoxic effects on human colon cancer (Col2) cells (IC50 = 12.3 μM; [11]), human liver carcinoma (HepG2) cells (IC50 value = 60.2 μM; [10]), and basal HER2-expressing human breast cancer cells (IC50 value = 58 μM; [17]).