Although rare genetic disorders, such as genetic mutations that involve in defective synthesis of parathyroid hormone (PTH), or abnormal parathyroid gland development or dysgenesis of thyroid glands associated with other developmental abnormalities, such as thymic hypoplasia, defects in the cardiac outflow tract, typically manifest in the neonatal or childhood period [1, 2], it is rarely reported as the etiologies of adult onset hypoparathyroidism [3–5]. This evidence concerns the gene PTH and hereditary disease.