Extensive studies have suggested that Nrf2 contributes to protection against various pathologies, including asthma [23–25], chronic obstructive pulmonary disease (COPD) [26], lung fibrosis [27], carcinogenesis [28], atherosclerosis [29], inflammatory disorders [30], and environmental oxidants, including hyperoxia [31, 32] and cigarette smoke [33]. Here, NFE2L2 is linked to asthma.