FLT4 and neoplasm: Univariate analysis showed decreased expression of all three factors when the distance from the tumor margin increased (p = 0.000, p = 0.029, and p = 0.000 for VEGF-C, VEGFR-1, and VEGFR-3, respectively), which was also associated with the distance (Spearman’s correlation test, correlation coefficient (cc) = 0.807, p = 0.000 for VEGF-C; cc = 0.647, p = 0.000 for VEGFR-1; cc = 0.643, p = 0.000 for VEGFR-3).