Confirming our gene list as involved with brain tumor development, ‘Glioma Invasiveness Signaling’ (CD44, F2R, ITGAV, MMP9, RHOC, RND2, RND3, TIMP3, TIMP4) and ‘Glioblastoma Multiforme Signaling’ (CDK6, CDKN1A, EGFR, ITPR2, MYC, RHOC, RND2, RND3, TCF3, WNT5A) were returned as significant pathways as well. This evidence concerns the gene TIMP3 and central nervous system cancer.