Several pathways known to be important to glioma development were also at the top of the significant canonical pathways list, including ‘WNT/beta-Catenin Signaling’ (CD44, CDH2, DVL3, LRP1, MYC, SOX4, SOX9, SOX13, TCF3, TCF4, TLE3, WNT5A) and ‘mTOR Signaling’ (EIF3B, EIF3E, EIF3F, EIF4A1, HIF1A, PRKD1, RHOC, RND2, RND3). The gene discussed is SOX9; the disease is glioma.