Alleles significantly underrepresented in RA patients (thus potentially protective) were HLA-DRB1*08 (OR = 0.42), HLA-DRB1*13 (OR = 0.58), HLA-DRB1*03 (OR = 0.51), HLA-DRB1*11 (OR = 0.54), HLA-DRB1*14 (OR = 0.58), HLA-DRB1*07 (OR = 0.66) (Table 2). Here, HLA-DRB1 is linked to rheumatoid arthritis.