In the cortex and hippocampus of male CHF mice, the analyzed proteins, such as APP, BACE1, APP C-Terminal fragments (CTFs), Bax, Bcl-2, total Tau (t-Tau) and phosphorylated Tau (p-Tau) did not exhibited any alterations when compared with the respective protein levels in brains of the SHAM group (Figure 6A, B). This evidence concerns the gene BCL2 and congestive heart failure.