We selected the three highest ranked potential regulating genes from the list in Table 3 for which there are known cell lines containing amplifications of these genes (CONAN - Cancer Genome Project, Wellcome Trust Sanger Institute: http://www.sanger.ac.uk/cgi-bin/genetics/CGP/conan/search.cgi); namely ERBB2 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 2), ARPC1A (actin related protein 2/3 complex subunit 1A) and FANCG (Fanconi anemia complementation group G). This evidence concerns the gene FANCG and Fanconi anemia.