The seven factors (history of hypertension, history of diabetes mellitus, a body temperature of >37.5°C, hs-CRP levels and P-selectin levels on days 1, 3 and 7) in the progressive and non-progressive groups which had significant differences were the independent variables and progression or non-progression following the occurrence of ischemic stroke was the dependent variable used to carry out binary logistic regression analysis. The gene discussed is CRP; the disease is ischemic stroke.