HIF-1α plays a certain role in lymphangiogenesis by closely correlating with lymphatic expression of VEGF-C in cancers, wound healing, and inflammation [7, 20, 21], and we found that deoxyshikonin upregulated the VEGF-C mRNA level during lymphangiogenesis in vitro (Figure 3(b)). This evidence concerns the gene HIF1A and cancer.