We stereotaxically injected 1 × 106 multiplicity of infection (m.o.i) lentiviral Aβ1–42 bilaterally into the hippocampus of 1 year old C57BL/6 and parkin−/− mice and 3 weeks later we injected (IP) 5 mg/kg Bosutinib once a day for 3 additional weeks. Here, PRKN is linked to infection.