Against the background of ischemic AKI, WJ-MSCs contribute to restoration of the biased balance of HGF/TGF-β1 during fibrogenesis via induction of native and foreign HGF synthesis in injured tubular cells at the initial stage of AKI, which consequently results in the EMT delay and alleviation of renal fibrosis. This evidence concerns the gene TGFB1 and acute kidney injury.