We demonstrated that WJ-MSCs can restore the disturbed balance of HGF/TGF-β1 during fibrogenesis via induction of native and foreign HGF synthesis in host renal TECs at the initial stage of ischemic AKI, as a result of which tubular EMT delay and rescue of renal fibrosis occur. The gene discussed is TGFB1; the disease is renal fibrosis.