DMD and Duchenne muscular dystrophy: These treated fibroblasts were then transduced with a lentivirus expressing MyoD under an inducible promoter to stimulate transdifferentiation into the myogenic lineage and dystrophin expression.30,31 Expression of myogenin (Figure 5b) and myosin heavy chain (Figure 5c) confirmed efficient transdifferentiation of wild-type and DMD patient fibroblasts.