Interestingly, this meta-analysis consisted of the Caucasian studies mentioned above [16-18,20-22] and found that the GSTP1 I105V polymorphism was associated with an increased risk for ESCC (1.4; 1.0 – 2.2) and not for EAC (1.2; 0.9 – 1.6). The gene discussed is GSTP1; the disease is esophageal squamous cell carcinoma.