In the setting of MI, chemokines that recruit PMNs to sites of ischemia include macrophage inflammatory protein-2α (MIP-2α, CXCL2, GRO β), leukotriene B4 (LTB4), CINC-1 (CXCL1, GRO α, KC), IL-8 (CXCL8), and complement 5a [18,19]. This evidence concerns the gene CXCL8 and ischemia.