It is noteworthy that some of these patients were affected by conditions that sometimes may present with autistic traits: (1) two cell lines were from patients with Angelman syndrome, a condition often considered in the differential diagnosis of Rett syndrome, who did not meet criteria for ASDs; and (2) a patient with a ZNF711 mutation who did not exhibit ASD features. This evidence concerns the gene ZNF711 and atypical Rett syndrome.