VEGFA and renal cell carcinoma: Succinate dehydrogenase mutations leading to the activation of a pseudohypoxic response, and in particular up-regulation of the vascular endothelial growth factor (VEGF) have been described in other tumors (PGL and renal cell carcinoma) (Ricketts et al., 2008; Pasini and Stratakis, 2009; Favier et al., 2012; Linehan and Ricketts, 2012).