More recently, the combination of high-resolution genome-wide copy-number analyses with global gene expression data has been used to develop integrated molecular portraits of the oncogenesis of KIT/PDGFRA-mutated GIST (Astolfi et al., 2010; Yang et al., 2010; Ylipaa et al., 2011). The gene discussed is KIT; the disease is gastrointestinal stromal tumor.