SOD1 and epilepsy: Oxidative stress in patients with epilepsy treated with AEDs was assessed by measuring serum, plasma, erythrocyte, leukocyte or urine markers of macromolecular damage (MDA, RCD, P-SH, 8-OHdG, 15F-2t-isoP) and antioxidative enzyme activity (SOD, GPX, CAT, GR) (Table 1).