Parkin also impacts other cellular pathways, including TNFα signalling (Müller-Rischart et al, 2013) and Wnt/β-catenin signalling (Rawal et al, 2009), and Parkin was also found to be a tumour suppressor (Poulogiannis et al, 2010; Veeriah et al, 2010). This evidence concerns the gene PRKN and neoplasm.