WNT5A and melanoma: This is probably why WNT‐5A acts as a tumor suppressor in breast cancer, colon cancer, thyroid cancer, liver cancer, and lymphoid malignancies (Dejmek et al., 2005a; Jiang et al., 2013; Jonsson et al., 2002; Kremenevskaja et al., 2005; Liu et al., 2008; Roman‐Gomez et al., 2007) but promotes tumor progression in malignant melanoma and gastric cancer (Da Forno et al., 2008; Kurayoshi et al., 2006; Weeraratna et al., 2002).