In the multivariate logistic regression model, MetS was independently associated with microalbuminuria (OR 1.25, 95% CI: 1.03 − 1.51, p = 0.02); however, the association between high CRP and microalbuminuria disappeared after adjustments were made for age, sex, and other possible risk factors for CKD (p = 0.34). This evidence concerns the gene CRP and metabolic syndrome.