In addition, miR-7 down-regulates EGFR mRNA and protein expression in cancer cell lines (lung, breast, and glioblastoma) and the AKT pathway [37,38] inhibiting schwannoma cell growth [39] and inducing cell cycle arrest and cell death, which suggests a negative regulatory mechanism acting on the MAPK pathway [40]. The gene discussed is AKT1; the disease is schwannoma.