Consistent with previous studies conducted with intestinal (T-cell) response against a heterogeneous array of wheat glutenin and α-, γ-, ω-gliadins, our results with IgG- and IgA-specific antibodies demonstrate that both sera with gluten-sensitivity/celiac disease and Crohn's disease and, to a much lesser degree, sera from healthy controls respond to a heterogeneous array of peptides and antigens. The gene discussed is CD79A; the disease is celiac disease.