The mean ODs for IgG antibodies against various wheat and associated peptides and antigens in healthy controls were compared to those in patients with Crohn's disease, obtaining the most significant P values with P < 0.0002 for prodynorphin, TG and WGA, as well as the least significant P values P < 0.4744 for glutenin, as are shown in Table 1. Here, PDYN is linked to Crohn disease.