Increased promoter recruitment of p50, HDAC1, HDAC2 and Sirt1 to the NF-kB-associated site A region of the mir-424-503 gene was found in cells following infection (Fig. 5A and 5B), as assessed by ChIP analysis using primers covering the NF-kB-binding region within the promoter. This evidence concerns the gene HDAC1 and infection.