A variant in MUC16 was evaluated as "polymorphism" by the Mutation Taster program, and expression of this gene in the thyroid was suggested to be considerably low based on several databases including BioGPS (http://biogps.org/), Cancer Genome Anatomy Project (http://cgap.nci.nih.gov/SAGE) and GeneHub-GEPIS (http://research-public.gene.com/Research/genentech/genehub-gepis/). This evidence concerns the gene MUC16 and cancer.