GAB2 and Senile plaques: As shown in Table 9, we found that RIN (r = 0.68, p<0.0001), sex (r = −0.28, p = 0.005), number of NFTs (r = −0.34, p = 0.0006) and number of senile plaques (r = −0.32, p = 0.001) were the best predictors of GAB2 mRNA levels in the temporal cortex whereas RIN (r = 0.76, p<0.0001) was the best predictor in cerebellum (a brain region much less affected by AD pathology than the cortex).