Cytokines and chemokines produced in EBV infection include IL-1β, IL-1receptor antagonist (IL-1Ra), IL-6, IL-8, IL-18, TNF-α, IFN- α/β, IFN-γ, monokine induced by IFN-γ, IFN-γ -inducible protein10 (IP-10) and granulocyte-macrophage colony-stimulating factor (9,20,27). This evidence concerns the gene TNF and Epstein-Barr virus infection.