The present study is planned to explore the importance of nuclear expression of cyclin B1 in metastasizing conventional SCC, that is well differentiated squamous cell carcinoma (WDSCC), moderately differentiated squamous cell carcinoma (MDSCC) and poorly differentiated squamous cell carcinoma (PDSCC) which have not been well-studied and also to study and compare with non-metastasizing variants of oral squamous cell carcinoma that is verrucous carcinoma. The gene discussed is CCNB1; the disease is oral cavity squamous cell carcinoma.