Among these genes, expression levels of NIN and LDLR mRNAs were significantly altered in the PCOS NAFLD group as compared to the non-PCOS NAFLD group (upregulated 1.65 fold with p < 0.009 and downregulated 0.51 fold with p < 0.04, respectively) (Figure 1). The gene discussed is LDLR; the disease is metabolic dysfunction-associated steatotic liver disease.