RHOA and infection: In our research, no significant difference was found in the infection rates of T. gondii tachyzoites in the cells overexpressed with RhoA or Rac1 wild-type proteins compared with those untransfected cells, while either overexpression of dominant negative mutants of RhoA or Rac1 or inhibition of endogenous RhoA or Rac1 in the host cell could significantly reduce cell invasion (Figure 7).