Genes regulated by NF-κB include those that are associated with inflammation (TNF, IL-6, and ICAM), cell survival (cIAP1/2, Bcl-2, and Bcl-xL), proliferation (CDK2), tumor progression (COX2), angiogenesis (VEGF), and also cell death (Fas and FasL) (Pahl, 1999). Here, NFKB1 is linked to neoplasm.