Others include Huntington’s disease (HD), dentatorubral-pallidoluysian atrophy (DRPLA), and six spinocerebellar ataxias [SCA1, SCA2, SCA3 (Machado-Joseph disease), SCA-6, SCA-7, SCA-17 (Truant et al., 2006; Orr and Zoghbi, 2007; La Spada and Taylor, 2010)]. Here, CASP3 is linked to Dentatorubral pallidoluysian atrophy.