Among all vegetables tested, Campari tomato suppressed diet-induced obesity in zebrafish, as judged by reductions in dyslipidemia and hepatic steatosis, and the downregulation of lipogenic genes such as SREBP1. This is the first study to use zebrafish for food component evaluation, and its results indicate that DIO-zebrafish are a powerful tool for identifying foods that can serve as natural medicines for the prevention or treatment of human hepatic steatosis. The gene discussed is SREBF1; the disease is fatty liver disease.