In the patients with neuropathologically verified FTD, although limited in the number of cases, NFL values were significantly higher in the tau-negative cases (median 1620; range 1050–5546 ng/L) compared with the tau-positive cases (median 665; range 250–1030 ng/L) (p=0.017), as shown in Figure 2. Here, MAPT is linked to frontotemporal dementia.