To determine whether VDR polymorphisms are linked to mortality in patients with AKI and use them as covariates for adjustment in multivariate analyses, we measured the two classic VDR polymorphisms, FokI and BsmI. FokI polymorphism results in a VDR molecule that is three amino acids shorter and that has higher biological activity than the wild-type protein. This evidence concerns the gene VDR and acute kidney injury.