An increased MYC mRNA expression was associated with deeper tumor extension (p = 0.006, η2 = 0.152, OP = 0.801), presence of lymph node metastasis (p = 0.023, η2 = 0.107, OP = 0.632), and distant metastasis (p<0.001, η2 = 0.788, OP = 1) (Table 2). Here, MYC is linked to neoplasm.