Firstly, as shown in Figure 2C, Kaplan-Meier and log-rank survival tests suggested that low- and high-MACC1 expression in HCC patients were associated with different survival time, with the OS of patients expressing low MACC1 in their HCC lesions surviving much longer that those with high MACC1 expression (P<0.001). Here, MACC1 is linked to hepatocellular carcinoma.