RB1 and gastrointestinal stromal tumor: Some of the miRNAs with recently identified targets in vitro in various tumor settings other than GIST include: miR-132 targeting Rb1[32], miR-193b targeting CCND1 and Mcl-1[33], miR-455-3p targeting Smad2[34], miR-125b targeting Mcl-1 and Bcl-2[35] and miR-542-5p targeting survivin[36].