Of those differentially expressed in our study, 14q32 miRNAs having confirmed targets include miR-127 (located within a CpG island and silenced in many cancers) targeting BCL-6[47], miR-154 targeting CCND2[48], miR-433 targeting HDAC6[49], miR-485-3p targeting NF-YB[50] and miR-539 targeting HLCS[51]. The gene discussed is HLCS; the disease is cancer.