In asthma patients, the percentage of MDSCs in the peripheral blood mononuclear cells (PBMCs) and the level of serum IL-10, IgE, EOS were both significantly elevated compared to normal controls, budesonide-treated alleviated asthma patients, and pneumonia patients (p<0.05), whereas those in the latter three groups showed no statistical differences (p>0.05). The gene discussed is IL10; the disease is pneumonia.