In addition, there was no difference in the expression of the active form of TGF-β1, VEGF, IL-10, extracellular HSP90α, CRT, HMGB1, CD47, and CD31 between the three types of ethanol-treated tumor cells (PANC/Mock, PANC/TGF-β, and PANC-1) (data not shown). Here, HMGB1 is linked to neoplasm.