For example, a large multicenter study reported adjusted AUCs of 0.78, 0.79, 0.77, and 0.80, respectively for urine albumin to creatinine ratio, urine neutrophil gelatinase-associated lipocalin (NGAL), urine IL-18, and plasma NGAL, as markers of AKI progression [6]. The gene discussed is LCN2; the disease is acute kidney injury.