The most notable associations among the ten previously GWAS-identified breast cancer susceptibility loci replicated in this study were with four FGFR2 SNPs (rs2981579, rs1219648, rs2420946 and rs2981582) and TNRC9-rs3803662 (observed P<7.0×10−10 and adjusted P<4.2×10−8) (Table S1). Here, TOX3 is linked to breast cancer.